Work package leaders

Rod Hose

The University of Sheffield

Rod is Professor of Computational Biomechanics at USFD, and will be the Principal Investigator (PI) for the project. He was the PI for VPH-Share, and was work package leader for valvular disease in euHeart. He was a co-author of the White Paper that launched the Virtual Physiological Human initiative.

After graduating in Mathematics from the University of Manchester, he joined Lucas Aerospace as a graduate apprentice engineer. From 1977 to 1992, he worked as a stress engineer and as a consultant structural analyst for several companies in the aerospace, motor vehicle and general engineering sectors.

During this period Rod also completed his PhD in Applied Mechanics at the University of Manchester Institute of Science and Technology.

He moved to Medical Physics at the University of Sheffield in 1994, where he was initially responsible for the development of undergraduate teaching in medical physics. He had a primary research interest in the computational analysis of heart valve prostheses.

Rod joined academia in 1992 as a lecturer in Aircraft. Rod is currently Professor of Computational Biomechanics in the Medical Physics Group in the Department of Cardiovascular Science.

Michel Rochette


Michel graduated from the University of Nice in 1990 where he obtained a PhD degree in mathematics. He founded CADOE (math company for 3D parametric simulation in 1994).

After the acquisition by ANSYS he has been leading the research for two main topics:

  1. Patient specific simulation

  2. Reduced Order Modelling.

His research team has two senior research engineers and five PhD students mainly focused on patient specific simulation.

As the leader of the ANSYS medical initiative, he manages partnership with academic Labs, University Hospitals, Medical software vendors, medical devices companies and medical imaging companies. He is in charge of the development and validation of medical vertical applications developed with partners.

Pim Tonino

Stichting Catharina Ziekenhuis

Pim Tonino is an interventional cardiologist and medical director of the Division of Cardiac monitoring (CCU) and first-aid heart. He is also still very active in scientific research after gaining a PhD at the Technical University of Eindhoven ( TUE) in 2010.

Education and experience

  • PhD (cum laude), TUE (2010), “Fractional Flow Reserve to Guide Percutaneous Coronary Intervention in Multi-Vessel Coronary Artery Disease

  • Currently training to become a cardiologist, Catharina Hospital, Eindhoven

  • Education: Medicine, Erasmus University, Rotterdam

Marian Bubak


Marian Bubak has an MSc degree in Technical Physics and PhD in Computer Science. He is an adjunct at the Institute of Computer Science and ACC Cyfronet AGH University of Science and Technology, Kraków, Poland. He is also a Professor of Distributed System Enginnering at the Universiteit van Amsterdam.

His research interests include parallel and distributed computing, grid systems, and e-science. He is the author of around 200 papers in this area, co-editor of 28 proceedings of international conferences and the Associate Editor of FGCS Grid Computing.

In the CrossGrid Project, he was the leader of the Architecture Team, the Scientific Coordinator of the K-WfGrid, the member of the Integration Monitoring Committee of theCoreGRID, and the WP leader in ViroLab and GREDIA EU IST projects. He is the strategic Planning Team leader in PL-Grid Project.

Titus Kühne

German Heart Institute Berlin

Titus is formally affiliated with the DHZB and the Charité, Medical University Berlin where he has a Professorship for non-invasive cardiovascular imaging and image based modelling.

His expertise in imaging of all age groups, image post-processing and image based modelling will be used in EurValve.

He also is the PI in the Cardioproof project that focused on model validation and the SystemsMedizin Initiative where he is heading one of the demonstrator projects.

Pascal Haigron

Universite de Rennes

Pascal Haigron is Professor at the University of Rennes 1, ESIR, Rennes, France. He received the PhD in Signal Processing and Telecommunications, from the University of Rennes 1, France, in 1993.

He is a member of the Laboratory of Signal and Image Processing – Laboratoire Traitement du Signal et de l’Image “LTSI” which is a joint Research Unit of the INSERM and the University of Rennes 1.

Since 2004, he is the leader of the research team IMPACT (Images and Models for Planning and AssistanCe to Therapy and surgery) at the LTSI.

His research experience is related to 3D shape reconstruction, virtual endoscopy, medical image processing and registration, decision support and image guided therapy.

Martin Falcke

Max Delbruck Centre for Molecular Medicine

Martin is head of the Group at MDC. He will be the principal investigator coordinating proteomic analysis and cellular simulations of excitation-contraction coupling and their integration into other model components.

Herman ter Horst


Herman is a Principal Scientist and works on decision support in healthcare applications with special focus on algorithms that realise machine learning and knowledge representation and reasoning.

He has been working on this topic in Philips-internal projects and also in European projects, in particular in VPH-Share and HeartCycle.

Jürgen Weese


Jürgen is a Research Fellow and was overall coordinator of euHeart. He works on medical image analysis related topics and is responsible for several Philips-internal projects. He will contribute to the image segmentation related tasks in EurValve.

Jürgen has been with Philips Research since 1994. He has been working in the area of medical imaging, computer assisted diagnosis and image guided therapy, and made numerous important contributions.

In particular, he introduced a software technology for the automatic generation of personalised heart and organ models from medical images that is a key component of an increasing number of innovative products. With his application-focused approach and contributions, he strongly influences the future development of cardio-vascular imaging solutions for diagnosis and therapy.

He is (co-)author of more than 120 articles in scientific journals and conference proceedings. His inventions resulted in over 30 granted US patents and 25 US patent applications.

Jürgen received numerous awards for important product transfers. In 2006, he received the Eduard Pannenborg Award for his outstanding research contributions.

Norman Briffa

Sheffield Teaching Hospitals NHS Foundation Trust

Norman is a Consultant Cardiac Surgeon based in the city of Sheffield and Honorary Senior Lecturer at the University of Sheffield.

He trained in medicine at the University of Sheffield. He trained in Cardiothoracic Surgery in the West Midlands and at Papworth Hospital in Cambridge. He was also a research Cardiothoracic Fellow at Stanford University in California.

Norman has been a cardiac surgeon for more than 20 years and has carried out thousands of heart operations. His specialist areas are Heart Valve Surgery, coronary bypass surgery and surgery for Atrial Fibrillation. He also specialises in the long term heart management of patients who have undergone heart surgery.

Cemil Göksu


Cemil graduated from the Ecole Centrale de Lyon where he obtained an engineering degree and a Master’s degree specialising in Bioengineering and Medical Imaging in 2001.

He joined the Image and Signal Processing Laboratory (LTSI Inserm U642) as a PhD student from 2001 to 2005. His research activities contributed to the design and development of an image-guided system for endovascular surgery.

Since 2007, he is the co-founder and CEO of Therenva, awarded by the French Ministry of Research at the 2007 Innovative Startup Contest and first prize winner of the 2008 AGBM Innovative Medical Device Technology Award.

Frans N. van de Vosse

Eindhoven University of Technology

Frans van de Vosse graduated in physics and is professor of Cardiovascular Biomechanics at the Eindhoven University of Technology and honorary professor of Cardiovascular Biomechanics at Maastricht University Medical Centre.

He is specialised in computational fluid dynamics and fluid structure interaction, experimental verification, and cardiovascular physiology. Current research relates to the computational and experimental biomechanical analysis of the cardiovascular system and its application to clinical diagnosis and intervention.

To advance the translation of research to the clinic he initiated and cofounded the School of Medical Physics and Engineering). He initiated and supervised a number of national and international projects or project work packages on the interface between technological and clinical research including EU-funded projects in FP6, Eureka andFP7.

He has (co-)supervised more than 30 PhD students and is (co-)author of over 120 scientific publications in internationally refereed technological as well as clinical journals.

His current research interests are related to the computational and experimental biomechanical analysis of the cardiovascular system and its application to clinical diagnosis and intervention, cardiovascular prostheses, extra corporeal systems and medical devices.

Ian Craddock

University of Bristol

Professor Ian Craddock is Director of the SPHERE, a £12M EPSRC-funded IRC. He works 60% of his time at the University leading SPHERE and also undertaking pioneering interdisciplinary research in medical imaging.

He founded a company that has attracted investment of £4M to undertake clinical trials and commercialise a cancer imaging device. He serves on the Steering Board of the University’s flagship Elizabeth Blackwell Health Research Institute.

For the rest of his time he is employed by Toshiba as Managing Director of their Telecommunications Research Lab in Bristol, responsible for a portfolio of both internal and collaborative communications, healthcare and smart city research.


Keith McCormack

Business Development Manager, the University of Sheffield

Karen El-Arifi

Project manager, the University of Sheffield